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Amorphous Calcium Phosphate

Naturally occurring in mineralized tissues, Amorphous Calcium Phosphate has been found more effective than alternative substances for revitalization of structures such as bones and teeth.


Calcium is an essential component of bones and teeth and has traditionally been introduced as an apatite or in the form of tricalcium phosphate. However, clinical studies have begun to show that the alternative form of Amorphous Calcium Phosphate (ACP) is more effective for a variety of purposes including:


  • Obstructing open tubules (pores)
  • Increasing osteoconductivity of fluoride, chlorhexidine, and others
  • Stimulating cell formation
  • Biodegrading rapidly to apatite for remineralization


ACP in Dentistry

Frequently used after procedures such as cleaning, bleaching, and the treatment of sensitive teeth, Amorphous Calcium Phosphate is applied in a variety of forms to the teeth. Use of ACP after these procedures has been noted to decrease sensitivity and aid in the healing of lesions and caries, as well as the stimulation of natural enamel growth. ACP breaks down and absorbs more rapidly than other traditional forms of calcium and phosphate leading to enhanced efficacy.


ACP for Osteoconduction

In addition to aiding in the restoration of calcium and phosphate in teeth and bones, ACP works to conduct other vital elements more effectively including Fluoride and Chlorhexidine.


Fluoride has long been recommended for the protection and vitalization of teeth and is included in many pastes, rinses, and even in drinking water. Studies documented by the American Dental Association (ADA) validate the increased fluoride uptake. By combining ACP and Fluoride into a paste, cream, or varnish, the same treatment time often more than doubles the Fluoride uptake into teeth greatly increasing the treatment effectiveness.


Chlorhexidine has been used as an antibacterial and antimicrobial in various dental products and treatments. The combination of ACP with Chlorhexidine has also been shown to be more effective than the rinse itself.


Other elements are being paired and studied leading to the development of creams, pastes, rinses, varnish, and innumerable other applications using ACP as a delivery vehicle. The effectiveness combined with rapid biodegradability makes this an effective option for dental treatments.